Cancer - Gynecology
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What are the most significant risk factors for gynecological cancers? Ovarian cancer risk factors: “Family history and genetics are linked to about 20 percent of ovarian cancercases,” said Dr. Frey. “Genetic conditions associated with gynecologic cancers include the BRCA1/2 gene and Lynch syndrome.” A positive BRCA1/2 test result indicates a mutation in one of the hereditary breast and ovarian cancer genes and, therefore, a significantly higher risk of developing breast cancer and ovarian cancer than someone who does not carry the mutation. However, not everyone with a positive result goes on to develop cancer. Lynch syndrome is a genetic condition that has a high risk of endometrial and colon cancer, as well as other cancers including ovarian cancer.
Other risk factors for ovarian cancer include:
History of endometriosis
Early menarche and late menopause (longer ovulation)
Polycystic Ovary Syndrome (PCOS)